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(2024)

Polymorphism in Norovirus Virus-Like Particles Exposed By Charge Detection Mass Spectrometry

Lohra M. Miller, Benjamin E. Draper, Joseph C.-Y. Wang, and Martin F. Jarrold. (under review)
Cryo-EM Structure and Molecular Dynamic Simulations Provide Explanations for the Enhanced Structural Stability and ATP Activity of the Pathologically Associated Human Mitochondrial Chaperonin Mutant

Aiza Syed, Jihang Zhai, Baolin Guo, Yuan Zhao*, Joseph Che-Yen Wang*, and Lingling Chen*. (*Co-corresponding), Structure, (DOI: https://doi.org/10.1016/j.str.2024.02.001)

(2023)

Structure of the Hepatitis B Virus capsid quasi-sixfold with a trapped C-terminal domain reveals capsid movements associated with domain exit

Christine Kim, Christopher J. Schlicksup, Carolina Pérez-Segura, Jodi A. Hadden-Perilla, Joseph Che-Yen Wang*, and Adam Zlotnick*. (*Co-corresponding), Journal of Biological Chemistry (https://doi.org/10.1016/j.jbc.2023.105104)
Protein structure predictions, atomic model building, and validation using a cryo-EM density map from Hepatitis B virus spherical subviral particle

Nadia DiNunno*, Emily Bianchini*, Haitao Liu, and Joseph Che-Yen Wang. (*Co-first author), Bio-Protocol, Jul. 13, (DOI: 10.21769/BioProtoc.4751)
Characterization of Intracellular Precore-derived Proteins and Their Functions in Hepatitis B Virus Infected Human Hepatocytes

Xupeng Hong, Emily Bianchini, Joseph Che-Yen Wang, and Jianming Hu. mBio, (DOIhttps://doi.org/10.1128/mbio.03501-22)

(2022)

Cryo-EM structures of human hepatitis B and woodchuck hepatitis virus small spherical subviral particles

 H Liu, X Hong, J Xi, S Menne, J Hu, and CY J Wang. Science Advance, Aug. 5 (DOI: 10.1126/sciadv.abo4184)
Region-Specific Hepatitis B Virus Genome Exposure from Nucleocapsid Modulated by Capsid Linker Sequence and Inhibitor – Implications for Uncoating

J Xi, X Cui, K Liu, H Liu, CY J Wang, and J Hu. Journal of Virology (DOI:https://doi.org/10.1128/jvi.00399-22)
Hypochlorous Acid as a Disinfectant for High-risk HPV: Insight into the mechanism of action

LI Robins, A Clark, PR Gafken, S Alam, J Milici, R Hassan, CY Wang, J Williams, C Meyers. Journal of Medical Virology
Mutations at the Alphavirus E2/E1 inter-dimer interface have host-specific phenotypes

SC Ren*, SA Qazi*, B Towell, JCY Wang, and S Mukhopadhyay. Journal of Virology (DOI:https://doi.org/10.1128/jvi.02149-21)

(2021)

Structure and RNA template requirements of Arabidopsis RNADEPENDENT RNA POLYMERASE 2

A Fukudome, J Singh, E Reddem, F Martinez-Marquez, S Wenzel, V Mishra, R Yan, M Shiozaki, Z Yu, J Wang, Y Takagi* and CS Pikaard*. PNAS ()

Controlled Modular Multivalent Presentation of CD40 Ligand on P22 Virus-Like Particles Leads to Tunable Amplification of CD40 Signaling

C Goodall, B Schwarz, E Selivanovitch, J Avera, JCY Wang, H Miettinen, T Douglas. ACS Applied Bio Materials (2021)

Sample Preparation using a Lipid Monolayer Method for Electron Crystallographic Studies

CD Truong, DR Williams, M Zhu, JCY Wang, PL Chiu. JOVE (2021).

Core Protein-Directed Antivirals and Importin β Can Synergistically Disrupt HBV Capsids

C Kim, L Barnes, C Schlicksup, A Patterson, B Bothner, M Jarrold, JCY Wang, and A Zlotnick. Journal of Virology (2021)

Structural basis for the structural dynamics of human mitochondrial chaperonin mHsp60 

JCY Wang*, L Chen* (*Co-corresponding).  Scientific Reports (2021)
Asymmetrizing an icosahedral virus capsid by hierarchical assembly of subunits with designed asymmetry 

Z Zhao, JCY Wang, M Zhang, N Lyktey, MF Jarrold, JC Jacobson, and A Zlotnick. Nature Communication (2021) 12:589 

 

(2020)

Virus Assembly Pathways: Straying Away but Not Too Far

K Bond, IB Tsvetkova, JCY Wang*, MF Jarrold*, and B Dragnea*. (*Co-corresponding). Small
Also, highlighted at Advance Science News
Revisiting an old friend: New findings in Alphavirus structure and assembly

JM Button, SA Qazi, JCY Wang, and S Mukhopadhyay. Current Opinion in Virology
Discovery of Exosomes From Tick Saliva and Salivary Glands Reveals Therapeutic Roles for CXCL12 and IL-8 in Wound Healing at the Tick-Human Skin Interface

W Zhou, F Tahir, JCY Wang, M Woodson, MB Sherman, S Karim, G Neelakanta, H Sultana. Frontiers in Cell and Developmental Biology
The integrity of the intradimer interface of the Hepatitis B Virus capsid protein dimer regulates capsid self-assembly

Z Zhao, JCY Wang, CP Segura, JA Hadden-Perilla, A Zlotnick. ACS Chemical Biology
Local stabilization of subunit-subunit contacts causes global destabilization of Hepatitis B virus capsids

CJ Schlicksup, P Laughlin, S Dunkelbarger, JCY Wang, A Zlotnick. ACS Chemical Biology
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